Ohjelmassa on kolme sessiota, kutsuttuja vierailevia ja paikallisia puhujia, iCAN- tutkimusprojektien esittelyjä ja posterinäyttely. Syöpäkeskuksen tieteellisen työryhmän jäsenet ovat valinneet osan suullisista esityksistä lähetettyjen abstraktien perusteella.
Vierailevat puhujat:
- Professori Anna Dimberg, Ruotsi
- Akatemian tutkija James Conway, Helsingin yliopisto
- Apulaisprofessori, LT, Anniina Färkkilä, Helsingin yliopisto
Programme
8.30–8.35: Opening words: Prof. and chair of the Scientific working group Teemu Murtola
Session 1 Chair: PhD, PI Kirsi Rautajoki
8.35–9.20 KEYNOTE TALK: prof. Anna Dimberg: tba
Department of Immunology, Genetics and Pathology, University of Uppsala, Sweden
9.20–9.32 Mohieddin Jafari: Shifting Beyond Classical Drug Synergy in Combinatorial Therapy through Solubility Alterations
Faculty of Medicine and Health Technology, Tampere University (Presentation selected based on a submitted abstract, 10 + 2 min)
9.32–9.42 Pitch talks (a 2 min)
- Lotta Isosaari: Development of advanced Brain Cancer-on-Chip: from proof-of-concept to modeling patient-derived glioblastoma behavior in a brain-mimetic 3D microenvironment
- Liang Zhang: RingNet: An Interactive Platform for Multi-Modal Data Visualization in Networks
- Göktug Karabiyik: Exploiting epigenetic susceptibilities in Atypical Teratoid/Rhabdoid tumors through chemical interventions
- Thomas Cecchetto: Inflammation and androgen deprivation cooperatively rewire prostate cancer epithelial identity
- Anja Hartewig: Integrative multi-modal analysis reveals the contribution of noncoding RNAs to post-treatment progression of IDH-mutant astrocytomas
9.45–10.30 Poster session and Coffee, tea and snacks (45 min)
10.30–10.50 PhD Elina Mäntylä: tba
Faculty of Medicine and Health Technology, Tampere University (Invited local speaker, 15’ + 5’)
10.50–11.15 Presentations selected based on submitted abstracts (a 10 + 2 min)
- Zhesi Zhang : MiREA: A Network-Based Tool for Edge-Based MicroRNA-oriented Enrichment Analysis
Faculty of Medicine and Health Technology, Tampere University - Uzma Hasan: Differential Migration of Glioblastoma and Gliosarcoma in 3D Matrix Model
Faculty of Medicine and Health Technology, Tampere University
11.15–12.05 Lunch break (50 min)
Session 2 Chair: ass. prof. Minna-Liisa Änkö
12.05–12.50 KEYNOTE TALK: Academy Research Fellow, James Conway: ECM spot arrays as a screening platform to assess cell-ECM interactions
Department of Biochemistry and Developmental Biology, University of Helsinki (30’+15’)
12.50–13.10 PhD Austin Evans: Bioengineering Tumor ECM‑Mimetic Biomaterial Platforms to Advance Predictive Oncology and Cancer Therapy, Faculty of Medicine and Health Technology, Tampere University (Invited local speaker, 15 ‘ + 5’)
13.10–13.22 Karoliina Salenius: Nationwide population-based cohort study identifies medical conditions preceding central nervous system tumors, Faculty of Medicine and Health Technology, Tampere University (Presentation selected based on a submitted abstract, 10 + 2 min)
13.25–13.35 Sanna Siltanen: Cancer research possibilities with FCBT, Director, Finnish Clinical Biobank Tampere, Pirha
13.35–13.55 MD, PhD Otso Arponen: Novel methods for evaluating treatment tolerability in older patients with cancer.
MET, Tampere University and Tampere University Hospital, Pirha (invited local speaker, 15’+5’)
13.5–14.15 Coffee break (20 min.)
Session 3. Chair: prof. Toni Seppälä
14.15–15.00: KEYNOTE TALK: ass. prof. Anniina Färkkilä: Unraveling the Determinants of Spatial Tumor Ecosystem in Ovarian Cancer: Insights into Immune Interactions and Therapeutic Opportunities (30’+15’)
Research Program for Systems Oncology (ONCOSYS) Program, Faculty of Medicine, University of Helsinki
15.00–15.20 MD, PhD Jussi Nikkola: Urine liquid biopsy for diagnosis and management of urothelial cancer
MET, Tampere University and Tampere University Hospital, Pirha (Invited local speaker, 15+5’)
15.20–16.00 Tampere iCAN docs’ presentations:
Lauri Ryyppö: Feasibility and interim results from the prospective international LS-URO study: urine tumor DNA-based screening for urothelial cancer in Lynch syndrome carriers (NCT06218433) (10 min+2 min)
Pitches (a 2 min.):
- Iida Koivisto: Identifying androgen deprivation-induced responses in prostate cancer with single cell multiomic analysis
- Alvar Saarinen: Hypoxia induces lipidomic shift in prostate cancer cells
- Tiia Nikupaavola: Inaccuracy in preoperative diagnostics: Tumor Microenvironment and Molecular Signatures Underlying Staging Transitions in Colorectal Cancer
- Jenni Keränen: Exploring the mechanical characteristics of tumour microenvironment in colorectal cancer.
Iida Salonen: Hypoxia and Associated Acidosis Shape Cell-Type Specific Myeloid Responses in Glioblastoma (10 min + 2 min.)
Pitches (a 2 min.):
- Kalle Hokkanen: More begets more: prior cancer history is an independent risk factor in Lynch syndrome
- Kiia Vaalavirta: Androgen receptor levels regulate dose-dependent morphological responses and gene expression in prostate cancer cells
- Jenni Rapakko: SRSF3 shapes the structure and processing of miR-17-92 cluster in colorectal cancer
- Maria Annala: Computational analysis of aberrant gene regulation in pediatric atypical teratoid/rhabdoid tumors
16.00 – 16.05 Closing remarks: ass. professor of cancer research Toni Seppälä
Organisers: Tays Cancer Centre in collaboration with the Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Pirha
Tarjolla kahvia, teetä ja pientä purtavaa.